Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568577 | 0.71 | CHRNB2 (0.44) | CHRNB2CHRNA4KDM4EALDH1A1KMT2A | |
| SCHEMBL17546667 | 0.60 | CYP19A1 (0.45) | CHRNB2CHRNA4KDM4EALDH1A1CYP19A1 | |
| SCHEMBL10640614 | 0.59 | CHRNB2 (0.48) | CHRNB2CHRNA4KDM4EMAPTKMT2A | |
| SCHEMBL21453950 | 0.59 | GPR3 (0.64) | ALDH1A1GPR3KMT2ASMN1; SMN2 | |
| SCHEMBL2524847 | 0.59 | CHRNB2 (0.52) | CHRNB2CHRNA4KDM4EALDH1A1MAPT | |
| SCHEMBL14940174 | 0.58 | MAPT (0.63) | KDM4EALDH1A1CYP19A1MAPTNPC1 | |
| SCHEMBL11629644 | 0.56 | CYP2A6 (0.48) | CHRNB2CHRNA4KDM4EALDH1A1CYP19A1 | |
| SCHEMBL27907518 | 0.55 | — | — | |
| SCHEMBL21261501 | 0.55 | CYP19A1 (0.46) | CHRNB2CHRNA4KDM4EALDH1A1CYP19A1 | |
| SCHEMBL29804975 | 0.55 | CHRNB2 (0.56) | CHRNB2CHRNA4ALDH1A1CYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064954-A1 | Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds | SPONDULI SERVICES, LTD. (AU) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064954-A1 | Cationic amphiphilic 1,4-dihydropyridine derivatives useful for delivery of nucleotide containing compounds | ACIN1, DNA2, KPNA1 | CHRNB2 1846/4885CHRNA4 597/4885KDM4E 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.