Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568657 | 0.84 | NR1I2 (0.65) | KEAP1NFE2L2KMT2AMEN1PTGER1 | |
| SCHEMBL699184 | 0.81 | KEAP1 (0.88) | KEAP1NFE2L2KMT2APPARG | |
| SCHEMBL28575718 | 0.79 | KEAP1 (0.61) | KEAP1NFE2L2KMT2AMEN1PPARG | |
| SCHEMBL28561073 | 0.79 | KEAP1 (0.61) | KEAP1NFE2L2KMT2AMEN1PPARG | |
| SCHEMBL6204399 | 0.78 | KEAP1 (0.67) | KEAP1NFE2L2KMT2AMEN1PPARG | |
| SCHEMBL14502622 | 0.77 | KEAP1 (0.66) | KEAP1NFE2L2KMT2AMEN1PPARG | |
| SCHEMBL10953009 | 0.76 | KEAP1 (0.56) | KEAP1NFE2L2KMT2AMEN1PTGER1 | |
| SCHEMBL5286157 | 0.76 | NR1I2 (0.76) | KEAP1NFE2L2KMT2AMEN1MAPT | |
| SCHEMBL28567580 | 0.75 | POLB (0.59) | KEAP1NFE2L2KMT2APPARGMAPT | |
| SCHEMBL28564469 | 0.74 | LMNA (0.54) | KEAP1NFE2L2KMT2AMEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010361-A2 | NITROGEN ATOM TRANSFER | YLEKTRA INC. (CA) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010361-A2 | NITROGEN ATOM TRANSFER | YLEKTRA INC. (CA) | 2003-02-06 | — | — | WO | disclosed |