Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27664301 | 0.85 | PPARG (0.56) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL27484451 | 0.84 | PPARG (0.68) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL31217586 | 0.81 | KDM4E (0.54) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL29802950 | 0.81 | PPARG (0.63) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL3395103 | 0.81 | PPARG (0.63) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL7538820 | 0.81 | PPARG (0.55) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL6747772 | 0.79 | KDM4E (0.59) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL19925815 | 0.78 | PPARG (0.69) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL24310220 | 0.78 | CYP11B1 (0.77) | PPARGKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL1650806 | 0.77 | ESR1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292589-A2 | METHODS FOR PRODUCING CHIRAL CHROMONES, CHROMANES, AMINO SUBSTITUTED CHROMANES AND INTERMEDIATES THEREFOR | MILLENIUM PHARMACEUTICALS, INC. (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001094335-A2 | METHODS FOR PRODUCING CHIRAL CHROMONES, CHROMANES, AMINO SUBSTITUTED CHROMANES AND INTERMEDIATES THEREFOR | ELI LILLY & COMPANY (US) | 2001-12-13 | — | — | WO | disclosed |