Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046436 | 0.83 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL7044435 | 0.79 | CNR1 (0.49) | CNR1ALPLCNR2 | |
| SCHEMBL7042652 | 0.79 | ALDH1A1 (0.42) | CNR1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL7046592 | 0.79 | CNR1 (0.61) | CNR1CNR2 | |
| SCHEMBL7044215 | 0.78 | CNR1 (0.61) | CNR1NPC1RAB9A | |
| SCHEMBL7046182 | 0.78 | PIN1 (0.42) | SMN1; SMN2TP53HPGDMEN1KMT2A | |
| SCHEMBL6552039 | 0.78 | CNR1 (0.47) | CNR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7044597 | 0.77 | CNR1 (0.63) | CNR1NPC1RAB9A | |
| SCHEMBL6552429 | 0.77 | CNR1 (0.63) | CNR1NPC1RAB9A | |
| SCHEMBL7041731 | 0.77 | CNR1 (0.47) | CNR1ALPLCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |