Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042652 | 0.89 | ALDH1A1 (0.42) | HPGDKDM4ESMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7044568 | 0.78 | CNR1 (0.48) | HPGDSMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL7046592 | 0.78 | CNR1 (0.61) | — | |
| SCHEMBL7047758 | 0.76 | KDM4E (0.51) | HPGDKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL7046176 | 0.72 | NPC1 (0.51) | HPGDKDM4ESMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL5274289 | 0.71 | KDM4E (0.58) | HPGDKDM4ESMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL7042639 | 0.69 | HPGD (0.52) | HPGDKDM4ESMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7044567 | 0.69 | CSNK2A2 (0.47) | — | |
| SCHEMBL11227523 | 0.69 | KDM4E (0.51) | HPGDKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6018249 | 0.69 | KDM4E (0.51) | HPGDKDM4ESMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |