Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573354 | 0.85 | HPGD (0.49) | RAB9ANPC1HPGDGSK3BHDAC3 | |
| SCHEMBL18917595 | 0.85 | L3MBTL1 (0.63) | RARBMMP1L3MBTL1PLA2G4BTSHR | |
| SCHEMBL28697442 | 0.83 | HDAC3 (0.54) | HPGDGSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL1742078 | 0.83 | TSHR (0.49) | RAB9ANPC1HPGDRARBL3MBTL1 | |
| SCHEMBL866784 | 0.82 | GSK3B (0.61) | RAB9ANPC1HPGDGSK3BHDAC3 | |
| SCHEMBL28933513 | 0.80 | TP53 (0.53) | HPGDGSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL28707265 | 0.80 | TP53 (0.53) | HPGDGSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL28706742 | 0.80 | TP53 (0.53) | HPGDGSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL28686349 | 0.80 | TP53 (0.53) | HPGDGSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL28691184 | 0.80 | TP53 (0.53) | HPGDGSK3BHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130232-A1 | Amidine derivatives, the preparation and use thereof as medicaments with LTB4 antagonistic effect | BOEHRINGER INGELHEIM KG (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6489365-B1 | LTB4-ANTAGONISTIC COMPOUNDS FOR TREATMENT OF INFLAMMATION, ALLERGY OR GASTROPATHY INDUCED BY NON-STEROIDAL ANTIINFLAMMATORY AGENTS IN A WARM-BLOODED ANIMALS | BOEHRINGER INGELHEIM KG (DE) | 2002-12-03 | — | — | US | disclosed |
| US-6037377-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS | BOEHRINGER INGELHEIM KG (DE) | 2000-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130232-A1 | Amidine derivatives, the preparation and use thereof as medicaments with LTB4 antagonistic effect | LTB4R2, LTB4R, LTA4H | RAB9A 2391/4885NPC1 3145/4885HPGD 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.