Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11120384 | 0.85 | MAOA (0.34) | MAPTALDH1A1 | |
| SCHEMBL11119917 | 0.82 | LMNA (0.40) | MAPTALDH1A1ALOX15RECQL | |
| SCHEMBL1201689 | 0.81 | KDM4E (0.40) | ESR1ESR2MAPTGAAALDH1A1 | |
| SCHEMBL11121382 | 0.77 | CDK1 (0.47) | MAPTGAA | |
| SCHEMBL1200431 | 0.76 | PTPN1 (0.45) | GAA | |
| SCHEMBL10606553 | 0.74 | AR (0.35) | MAPTTSHR | |
| SCHEMBL29085240 | 0.72 | CYP19A1 (0.47) | MAPTGAARECQL | |
| SCHEMBL1200443 | 0.70 | ESR1 (0.55) | ESR1ESR2MAPTGAARECQL | |
| SCHEMBL11259686 | 0.67 | ESR1 (0.40) | ESR1ESR2MAPTGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11051998 | 0.66 | ESR1 (0.39) | ESR1ESR2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294374-A1 | FLAVONE/FLAVANONE DERIVATIVES FOR THE SYSTEMIC TREATMENT AND PROPHYLAXIS OF UV-INDUCED DERMATOSES | Krutmann, Jean (DE) | 2003-03-26 | — | — | EP | claimed |
| WO-2002000214-A1 | FLAVONE/FLAVANONE DERIVATIVES FOR THE SYSTEMIC TREATMENT AND PROPHYLAXIS OF UV-INDUCED DERMATOSES | KRUTMANN JEAN (DE) | 2002-01-03 | — | — | WO | claimed |
| EP-1294374-A1 | FLAVONE/FLAVANONE DERIVATIVES FOR THE SYSTEMIC TREATMENT AND PROPHYLAXIS OF UV-INDUCED DERMATOSES | Krutmann, Jean (DE) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000214-A1 | FLAVONE/FLAVANONE DERIVATIVES FOR THE SYSTEMIC TREATMENT AND PROPHYLAXIS OF UV-INDUCED DERMATOSES | KRUTMANN JEAN (DE) | 2002-01-03 | — | — | WO | disclosed |
| US-4636569-A | Pharmaceutical compositions containing compounds with a flavanone skeleton, process for the preparation of the said compound and novel compounds obtained | INVERNI DELLA BEFFA S.P.A. (IT) | 1987-01-13 | — | — | US | disclosed |
| EP-0122053-A2 | Pharmaceutical compositions containing compounds with a flavanone skeleton and process for the preparation of said compounds | INVERNI DELLA BEFFA S.P.A. (IT) | 1984-10-17 | — | — | EP | disclosed |