Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295058 | 0.79 | TAS1R3 (0.37) | SLC6A4 | |
| SCHEMBL8372279 | 0.79 | TRPA1 (0.39) | SLC6A4LMNA | |
| SCHEMBL2712117 | 0.78 | L3MBTL1 (0.33) | SLC6A4LMNA | |
| SCHEMBL17295109 | 0.77 | IDO1 (0.35) | CCR2AR | |
| SCHEMBL31451660 | 0.77 | SLC6A4 (0.35) | SLC6A4LMNASTK17BAR | |
| SCHEMBL31038741 | 0.77 | LOXL2 (0.41) | SLC6A4 | |
| SCHEMBL6513914 | 0.77 | SLC6A4 (0.35) | SLC6A4LMNASTK17BAR | |
| SCHEMBL6520589 | 0.77 | CYP4F2 (0.42) | SLC6A4LMNASTK17BAR | |
| SCHEMBL896163 | 0.76 | HTT (0.42) | — | |
| SCHEMBL22826739 | 0.76 | CNR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148972-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | Cardioxyl Pharmaceuticals Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015183839-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2015-12-03 | — | — | WO | disclosed |
| EP-1296971-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001081332-A2 | 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2001-11-01 | — | — | WO | disclosed |