Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.55 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045540 | 1.00 | MEN1 (0.56) | MEN1KMT2APDE7APDE7BMAPT | |
| SCHEMBL6744948 | 0.86 | MAPT (0.59) | MEN1KMT2APDE7APDE7BMAPT | |
| SCHEMBL21571668 | 0.84 | FAAH (0.48) | MEN1KMT2AMAPTFAAHMGLL | |
| SCHEMBL6747346 | 0.83 | ALDH1A1 (0.57) | MEN1KMT2APDE7APDE7BMAPT | |
| SCHEMBL16262194 | 0.81 | SIRT6 (0.54) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16262196 | 0.81 | SIRT6 (0.54) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7046342 | 0.80 | SMN1; SMN2 (0.43) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16262847 | 0.77 | LMNA (0.54) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16262843 | 0.77 | LMNA (0.54) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20339055 | 0.77 | MAPT (0.48) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207866-A1 | Drugs useful for the treatment of diseases or disorders of the central nervous system. | PHARMACIA & UPJOHN COMPANY | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207866-A1 | Drugs useful for the treatment of diseases or disorders of the central nervous system. | PMP22, NLN, INA | MEN1 403/4885KMT2A 3767/4885PDE7A 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.