Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720844 | 0.79 | THRA (0.51) | — | |
| SCHEMBL2886641 | 0.77 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL8555091 | 0.73 | NPC1 (0.53) | RAB9ASMN1; SMN2NPC1PTGER1 | |
| SCHEMBL17802767 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL839875 | 0.73 | HCAR3 (0.56) | RAB9ASMN1; SMN2NPC1MAPTHCAR3 | |
| SCHEMBL16396946 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL17908114 | 0.73 | PTGER1 (0.56) | RAB9ASMN1; SMN2NPC1MAPTPTGER1 | |
| SCHEMBL16396789 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL417903 | 0.72 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL565748 | 0.72 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |