Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | CFB | P00751 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573354 | 0.83 | TAAR1 (0.40) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL698787 | 0.81 | CYP19A1 (0.43) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL697634 | 0.81 | CYP19A1 (0.37) | CYP19A1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL697369 | 0.80 | ADRA2A (0.43) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL698375 | 0.77 | CYP19A1 (0.40) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL699180 | 0.75 | CYP19A1 (0.47) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL27733474 | 0.75 | CYP19A1 (0.47) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL697917 | 0.73 | CYP19A1 (0.38) | CYP19A1TAAR1 | |
| SCHEMBL706070 | 0.73 | CYP19A1 (0.48) | ADRA2AADRA1AADRA2CADRA1DADRA1B | |
| SCHEMBL696761 | 0.73 | TAAR1 (0.40) | CYP19A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |