Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697512 | 0.83 | CYP19A1 (0.51) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7914818 | 0.83 | CYP19A1 (0.51) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL697816 | 0.81 | CYP19A1 (0.51) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL698443 | 0.79 | CYP19A1 (0.40) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL698788 | 0.76 | CYP19A1 (0.47) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL697855 | 0.76 | CYP19A1 (0.40) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL697369 | 0.76 | ADRA2A (0.43) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL704581 | 0.75 | ADRA2A (0.37) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL698375 | 0.74 | CYP19A1 (0.40) | CYP19A1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL697717 | 0.72 | CYP19A1 (0.51) | CYP19A1CYP3A4ADRA2AADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |