Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MAOA | P21397 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | IL2 | P60568 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | XDH | P47989 | 1/20 | 0.66 |
| ▸ | BCL2 | P10415 | 1/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041317 | 0.94 | XDH (0.60) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7044922 | 0.89 | ALDH1A1 (0.70) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL571576 | 0.87 | XDH (0.84) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7045859 | 0.82 | RAB9A (0.80) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5814089 | 0.81 | XDH (0.78) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10441792 | 0.81 | MAPT (0.74) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL738941 | 0.80 | ALDH2 (0.80) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14070597 | 0.80 | ALDH2 (0.80) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30527918 | 0.80 | ALDH2 (0.80) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Isoformonentin SCHEMBL73338 | 0.80 | XDH (1.00) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212312-B1 | NOVEL DERIVATIVES OF FLAVONES, XANTHONES AND COUMARINS | INDENA SPA (IT) | 2003-04-02 | — | — | EP | disclosed |
| CN-1371371-A | Novel derivatives of flavones, xanthones and coumarins | INDENA SPA (IT) | 2002-09-25 | — | — | CN | disclosed |
| EP-1212312-A1 | NOVEL DERIVATIVES OF FLAVONES, XANTHONES AND COUMARINS | INDENA S.p.A. (IT) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001017985-A1 | NOVEL DERIVATIVES OF FLAVONES, XANTHONES AND COUMARINS | INDENA S.P.A. (IT) | 2001-03-15 | — | — | WO | disclosed |