Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711759 | 0.77 | METAP2 (0.36) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL9773297 | 0.71 | RAB9A (0.47) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL3714915 | 0.70 | METAP1 (0.40) | KMT2AMETAP1MAPK9MAPK10MAPK8 | |
| SCHEMBL2762714 | 0.69 | RAB9A (0.51) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL7964249 | 0.68 | TSHR (0.50) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL10151029 | 0.68 | METAP2 (0.39) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL4515967 | 0.67 | CYP19A1 (0.47) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL18611536 | 0.66 | MAPT (0.57) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 | |
| SCHEMBL679357 | 0.65 | METAP2 (0.46) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL29165029 | 0.65 | CYP2A6 (0.41) | RAB9AKDM4ENPC1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166689-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | CLARIO TECH LIMITED (GB) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166689-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD11B2 | RAB9A 3689/4885KDM4E 3109/4885NPC1 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.