Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17966385 | 0.91 | MEN1 (0.63) | MEN1KMT2AMRGPRX4HPGDNR4A2 | |
| SCHEMBL30307916 | 0.86 | MEN1 (0.61) | MEN1KMT2AMRGPRX4HPGDNR4A2 | |
| SCHEMBL4876543 | 0.86 | MEN1 (0.61) | MEN1KMT2AMRGPRX4HPGDNR4A2 | |
| SCHEMBL6865198 | 0.86 | HPGD (0.71) | MEN1KMT2AMRGPRX4HPGDLMNA | |
| SCHEMBL16616383 | 0.84 | HPGD (0.53) | MRGPRX4HPGDLMNANPC1RAB9A | |
| SCHEMBL27527174 | 0.83 | MEN1 (0.54) | MEN1KMT2AMRGPRX4HPGDNR4A2 | |
| SCHEMBL13117262 | 0.81 | CYP1A2 (0.53) | MEN1KMT2ANR4A2LMNAMCL1 | |
| SCHEMBL2227072 | 0.81 | LMNA (0.56) | MEN1KMT2AMRGPRX4HPGDNR4A2 | |
| SCHEMBL3965806 | 0.80 | EGFR (0.64) | MEN1KMT2AMRGPRX4HPGDNR4A2 | |
| SCHEMBL3960943 | 0.80 | NR4A2 (0.58) | MEN1KMT2AMRGPRX4HPGDNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |