Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.64 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL5874129 | 0.97 | LDHA (0.60) | LDHASRRTSHRGABRA5GABRB2 | |
| Malonic Acid SCHEMBL5874133 | 0.97 | LDHA (0.60) | LDHASRRTSHRGABRA5GABRB2 | |
| Malonic Acid SCHEMBL6671875 | 0.90 | LDHA (0.60) | LDHASRRTSHRGABRA5GABRB2 | |
| Malonic Acid SCHEMBL5874600 | 0.88 | LDHA (0.50) | LDHASRRTSHRGABRA5GABRB2 | |
| Malonic Acid SCHEMBL2950460 | 0.88 | LDHA (0.50) | LDHASRRTSHRGABRA5GABRB2 | |
| Malonic Acid SCHEMBL17371700 | 0.84 | — | — | |
| Malonic Acid SCHEMBL338744 | 0.84 | — | — | |
| Malonic Acid SCHEMBL28215418 | 0.81 | LDHA (0.82) | LDHASRRTSHRPMP22LMNA | |
| Malonic Acid SCHEMBL1332554 | 0.80 | — | — | |
| Malonic Acid SCHEMBL336 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699079-B1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES COMPRISING GENETIC MATERIALS | DOW CHEMICAL CO (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6312679-B1 | Dense star polymer conjugates as dyes | THE DOW CHEMICAL COMPANY | 2001-11-06 | — | — | US | disclosed |
| US-6177414-B1 | POLYMAMINOAMIDE DENDRIMER STAR POLYMER CARRYING SALICYLIC ACID MOIETIES; DRUG DELIVERY | THE DOW CHEMICAL COMPANY | 2001-01-23 | — | — | US | disclosed |
| US-5714166-A | Bioactive and/or targeted dendrimer conjugates | THE DOW CHEMICAL COMPANY (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0271180-B2 | Starburst conjugates | DOW CHEMICAL CO (US) | 1997-06-18 | — | — | EP | disclosed |
| US-5527524-A | AGRICULTURAL, PHARMACEUTICAL, DRUG DELIVERY | THE DOW CHEMICAL COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0699079-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1995024221-A1 | BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5338532-A | Star polymer as carrier for drugs, agricultural compounds | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0271180-A1 | Starburst conjugates | THE DOW CHEMICAL COMPANY (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988001179-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |
| WO-1988001178-A1 | STARBURST CONJUGATES | THE DOW CHEMICAL COMPANY (US) | 1988-02-25 | — | — | WO | disclosed |