Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL5874600 | 1.00 | LDHA (0.50) | LDHASRRALDH1A1EPHX1CA2 | |
| Malonic Acid SCHEMBL6671875 | 0.91 | LDHA (0.60) | LDHASRRALDH1A1SMN1; SMN2CXCR4 | |
| Malonic Acid SCHEMBL7046147 | 0.88 | LDHA (0.64) | LDHASRREPHX1GABRA5GABRB2 | |
| Acetoacetic Acid SCHEMBL28315277 | 0.85 | ALDH1A1 (0.41) | LDHASRRALDH1A1EPHX1CA2 | |
| Malonic Acid SCHEMBL5874129 | 0.85 | LDHA (0.60) | LDHASRREPHX1SMN1; SMN2CXCR4 | |
| Malonic Acid SCHEMBL5874133 | 0.85 | LDHA (0.60) | LDHASRREPHX1SMN1; SMN2CXCR4 | |
| Piperidine SCHEMBL11192905 | 0.83 | ALDH1A1 (0.50) | ALDH1A1EPHX1CA2CHKASMN1; SMN2 | |
| Pyrrolidine SCHEMBL10413119 | 0.83 | FFAR3 (0.56) | ALDH1A1EPHX1CA2CHKASMN1; SMN2 | |
| Succinic Acid SCHEMBL5874137 | 0.83 | LMNA (0.50) | ALDH1A1CA2CHKASMN1; SMN2CXCR4 | |
| Succinic Acid SCHEMBL5874145 | 0.83 | LMNA (0.50) | ALDH1A1CA2CHKASMN1; SMN2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561830-A | Synthesis method of necrotic sulfonamide analogue | 南京安纳医药科技有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118561830-A | Synthesis method of necrotic sulfonamide analogue | 南京安纳医药科技有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118561830-A | Synthesis method of necrotic sulfonamide analogue | 南京安纳医药科技有限公司 | 2024-08-30 | — | — | CN | disclosed |
| EP-1648867-B1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON INC (US) | 2013-09-04 | — | — | EP | disclosed |
| US-8367828-B2 | PPAR active compounds | PLEXXIKON INC. (US) | 2013-02-05 | — | — | US | disclosed |
| CN-102875441-A | Plexxikon inc | PLEXXIKON INC | 2013-01-16 | — | — | CN | disclosed |
| WO-2010144959-A1 | ANALOGUES OF ANTI-FIBROTIC AGENTS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-12-23 | — | — | WO | disclosed |
| US-20100210036-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. | 2010-08-19 | — | — | US | disclosed |
| US-7723374-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7572806-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| CN-1845898-A | PPAR active compounds | PLEXXIKON INC (US) | 2006-10-11 | — | — | CN | disclosed |
| EP-1648867-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2006-04-26 | — | — | EP | disclosed |
| US-20050288354-A1 | PPAR active compounds | PLEXXIKON, INC. | 2005-12-29 | — | — | US | disclosed |
| US-20050038246-A1 | PPAR active compounds | PLEXXIKON, INC. | 2005-02-17 | — | — | US | disclosed |
| WO-2005009958-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4088496-A | SILVER SALT, DEVELOPER, BINDER AND AN ACTIVATOR, THE ACID PORTION OF WHICH IS 2-CARBOXYCARBOXAMIDE | EASTMAN KODAK COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4060420-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4012260-A | THIAZOLINIUM COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038246-A1 | PPAR active compounds | PPARG, PPARD, PPARA | LDHA 3553/4885SRR 2622/4885ALDH1A1 1171/4885 |
| US-20050288354-A1 | PPAR active compounds | PPARG, PPARD, PPARA | LDHA 3553/4885SRR 2622/4885ALDH1A1 1171/4885 |
| US-20100210036-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARD, PPARA | LDHA 3553/4885SRR 2622/4885ALDH1A1 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.