Malonic Acid

Malonic Acid

SCHEMBL5874600

C1CCNCC1.C1CCNCC1.O=C(O)CC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.50
SRR Q9GZT4 1/20 0.50
ALDH1A1 P00352 1/20 0.50
EPHX1 P07099 2/20 0.37
CA2 P00918 1/20 0.36
CHKA P35790 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
CXCR4 P61073 1/20 0.35
GABRA5 P31644 3/20 0.35
GABRB2 P47870 3/20 0.35
TSHR P16473 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRA4 P48169 2/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL2950460 1.00 LDHA (0.50) LDHASRRALDH1A1EPHX1CA2
Malonic Acid SCHEMBL6671875 0.91 LDHA (0.60) LDHASRRALDH1A1SMN1; SMN2CXCR4
Malonic Acid SCHEMBL7046147 0.88 LDHA (0.64) LDHASRREPHX1GABRA5GABRB2
Acetoacetic Acid SCHEMBL28315277 0.85 ALDH1A1 (0.41) LDHASRRALDH1A1EPHX1CA2
Malonic Acid SCHEMBL5874129 0.85 LDHA (0.60) LDHASRREPHX1SMN1; SMN2CXCR4
Malonic Acid SCHEMBL5874133 0.85 LDHA (0.60) LDHASRREPHX1SMN1; SMN2CXCR4
Piperidine SCHEMBL11192905 0.83 ALDH1A1 (0.50) ALDH1A1EPHX1CA2CHKASMN1; SMN2
Pyrrolidine SCHEMBL10413119 0.83 FFAR3 (0.56) ALDH1A1EPHX1CA2CHKASMN1; SMN2
Succinic Acid SCHEMBL5874137 0.83 LMNA (0.50) ALDH1A1CA2CHKASMN1; SMN2CXCR4
Succinic Acid SCHEMBL5874145 0.83 LMNA (0.50) ALDH1A1CA2CHKASMN1; SMN2CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed
US-4088496-A SILVER SALT, DEVELOPER, BINDER AND AN ACTIVATOR, THE ACID PORTION OF WHICH IS 2-CARBOXYCARBOXAMIDE EASTMAN KODAK COMPANY (US) 1978-05-09 US disclosed
US-4060420-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1977-11-29 US disclosed
US-4012260-A THIAZOLINIUM COMPOUNDS EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed