Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044199 | 0.89 | S1PR1 (0.52) | NPC1RAB9ACNR1HPGDTSHR | |
| SCHEMBL7043396 | 0.88 | CNR1 (0.61) | NPC1RAB9ACNR1HPGDTSHR | |
| SCHEMBL7044676 | 0.82 | CNR1 (0.54) | NPC1RAB9ACNR1HPGDTSHR | |
| SCHEMBL7043234 | 0.77 | CNR1 (0.60) | NPC1RAB9ACNR1HPGDTSHR | |
| SCHEMBL7044597 | 0.77 | CNR1 (0.63) | NPC1RAB9ACNR1 | |
| SCHEMBL6552429 | 0.77 | CNR1 (0.63) | NPC1RAB9ACNR1 | |
| SCHEMBL7047758 | 0.77 | KDM4E (0.51) | CNR1HPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7044215 | 0.76 | CNR1 (0.61) | NPC1RAB9ACNR1 | |
| SCHEMBL7044204 | 0.73 | CNR1 (0.58) | NPC1RAB9ACNR1HPGDTSHR | |
| SCHEMBL7046182 | 0.72 | PIN1 (0.42) | HPGDTSHRSOAT1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |