Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046408 | 0.82 | FABP1 (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28971693 | 0.82 | CLK4 (0.52) | KDM4ERAB9AMEN1KMT2APOLB | |
| SCHEMBL30854998 | 0.75 | GAA (0.51) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL30854951 | 0.75 | NCF1 (0.50) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL30854968 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL4722379 | 0.71 | — | — | |
| SCHEMBL30855014 | 0.71 | MTNR1A (0.53) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30854991 | 0.71 | NPC1 (0.51) | KDM4EALDH1A1RAB9APOLBMAPT | |
| SCHEMBL13403330 | 0.70 | RAB9A (0.50) | KDM4EALDH1A1HPGDRAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL14744482 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1RAB9APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011573-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-02-09 | — | — | WO | disclosed |