SCHEMBL70469

SCHEMBL70469

COc1c(O)ccc(O)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.44
MAPK1 P28482 3/20 0.44
TDP1 Q9NUW8 2/20 0.42
CA1 P00915 3/20 0.41
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA2 P00918 2/20 0.41
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
TPMT P51580 1/20 0.38
MAOB P27338 1/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5992537 0.86 CYP3A4 (0.52) CYP3A4MAPK1TDP1CA1GAA
SCHEMBL3384067 0.84 CYP3A4 (0.39) CYP3A4MAPK1TDP1CA1GAA
SCHEMBL9035273 0.84 MAPT (0.44) CYP3A4MAPK1TDP1CA1CA2
SCHEMBL29403778 0.81 TDP1 (0.52) CYP3A4MAPK1TDP1CA1GAA
SCHEMBL69925 0.81 TDP1 (0.52) CYP3A4MAPK1TDP1CA1GAA
SCHEMBL17744214 0.78 ALDH1A1 (0.50) CYP3A4MAPK1TDP1CA1GAA
SCHEMBL31269431 0.78 CA1 (0.58) TDP1CA1CA12CA7CA9
SCHEMBL6924772 0.78 TDP1 (0.51) TDP1CA1CA12CA7CA9
SCHEMBL1748844 0.78 RAB9A (0.42) CYP3A4MAPK1TDP1CA1CA12
SCHEMBL3432498 0.78 CA1 (0.58) TDP1CA1CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP3A4 2028/4885MAPK1 3382/4885TDP1 3534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.