Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70469 | 0.84 | CYP3A4 (0.44) | CYP3A4MAPK1TDP1MGAMGAA | |
| SCHEMBL14405259 | 0.81 | ALDH1A1 (0.36) | CYP3A4MAPK1TDP1MGAMGAA | |
| SCHEMBL4294248 | 0.79 | MAOA (0.44) | CYP3A4TDP1MAOASCN5AESR1 | |
| SCHEMBL29421886 | 0.79 | MAOA (0.44) | CYP3A4TDP1MAOASCN5AESR1 | |
| SCHEMBL9035273 | 0.78 | MAPT (0.44) | CYP3A4MAPK1TDP1ALOX15MAOB | |
| SCHEMBL1053291 | 0.77 | TP53 (0.43) | CYP3A4MAPK1TDP1MGAMGAA | |
| SCHEMBL768018 | 0.77 | SCN5A (0.52) | CYP3A4TDP1MAOASCN5AESR1 | |
| SCHEMBL21567219 | 0.77 | L3MBTL1 (0.41) | CYP3A4MAPK1GAAKDM4EALDH1A1 | |
| SCHEMBL25276594 | 0.74 | ALDH1A1 (0.42) | CYP3A4TDP1MGAMGAASI | |
| SCHEMBL931100 | 0.74 | CA2 (0.35) | MAPK1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188264-A2 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009035150-A2 | 4-PHENYL-5-HYDROXY-3(2H)-PYRIDAZINONE DERIVATIVES AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-03-19 | — | — | WO | disclosed |