Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSPO | P30536 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484433 | 0.82 | TDP1 (0.60) | ALDH1A1HTTSMN1; SMN2ACHELDHA | |
| SCHEMBL3716942 | 0.81 | TAS2R14 (0.55) | ALDH1A1ACHEALOX5MEN1KMT2A | |
| SCHEMBL7047446 | 0.79 | APLNR (0.55) | ALDH1A1HTTSMN1; SMN2ACHEAPLNR | |
| SCHEMBL11437372 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HTTSMN1; SMN2ACHEAPLNR | |
| SCHEMBL4199035 | 0.79 | HTT (0.54) | ALDH1A1HTTSMN1; SMN2ACHELDHA | |
| SCHEMBL18942071 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2ACHELDHA | |
| SCHEMBL16772806 | 0.79 | ALOX5 (0.58) | ALDH1A1HTTSMN1; SMN2ALOX5TDP1 | |
| Oxalic Acid SCHEMBL8497670 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2ACHELDHA | |
| SCHEMBL27995373 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2ACHEAPLNR | |
| SCHEMBL2343977 | 0.77 | ALOX5 (0.57) | ALDH1A1HTTSMN1; SMN2ALOX5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111353-A1 | N-SUBSTITUTED PIPERIDINE DERIVATIVES AS SEROTONIN RECEPTOR AGENTS | ACADIA PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |