SCHEMBL7047504

SCHEMBL7047504

COc1cccc(F)c1OC(=O)c1c2ccccc2nc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
RAB9A P51151 2/20 0.46
NPC1 O15118 2/20 0.46
POLB P06746 3/20 0.45
MAPT P10636 3/20 0.45
ALDH1A1 P00352 1/20 0.45
ALOX15 P16050 1/20 0.44
HTT P42858 1/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
CDK9 P50750 1/20 0.42
DYRK1A Q13627 1/20 0.42
TACR3 P29371 2/20 0.41
SLC2A1 P11166 1/20 0.41
SLC2A4 P14672 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TUBB4A P04350 1/20 0.41
TUBB P07437 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7795326 0.88 KMT2A (0.44) KMT2ARAB9APOLBMAPTALDH1A1
SCHEMBL8333267 0.83 RAB9A (0.41) KMT2ARAB9ANPC1POLBMAPT
SCHEMBL7787062 0.83 DYRK1A (0.51) KMT2ARAB9ANPC1POLBMAPT
SCHEMBL6584296 0.80 KMT2A (0.40) KMT2APOLBMAPTALDH1A1MEN1
SCHEMBL8741771 0.78 DYRK3 (0.48) KMT2ARAB9ANPC1POLBMAPT
SCHEMBL4421304 0.77 KMT2A (0.50) KMT2APOLBMAPTALDH1A1HTT
SCHEMBL38661829 0.76 MEN1 (0.49) KMT2APOLBMAPTALDH1A1HTT
SCHEMBL1054774 0.76 MEN1 (0.49) KMT2APOLBMAPTALDH1A1HTT
SCHEMBL6584034 0.76 GRM2 (0.45) KMT2ARAB9ANPC1POLBMAPT
SCHEMBL7796549 0.76 GRM2 (0.45) KMT2ARAB9ANPC1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609885-B1 Acridinium compounds and conjugates thereof MOCHIDA PHARM CO LTD (JP) 2003-04-16 EP disclosed
US-5594112-A CHEMILUMINESCENCE LABEL MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1997-01-14 US disclosed
US-5438139-A Chemiluminescent; useful as immunolochemical, DNA probe and receptor bininding assays MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1995-08-01 US disclosed
EP-0609885-A1 Acridinium compounds and conjugates thereof MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1994-08-10 EP disclosed