Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458161 | 0.79 | MEN1 (0.57) | KMT2AMEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL7993963 | 0.79 | MEN1 (0.57) | KMT2AMEN1ALDH1A1CYP1A2THRB | |
| Bicarbonate SCHEMBL5407657 | 0.79 | HTT (0.41) | KMT2AMEN1ALDH1A1ABCC4MAPT | |
| Bicarbonate SCHEMBL5407661 | 0.79 | HTT (0.41) | KMT2AMEN1ALDH1A1ABCC4MAPT | |
| SCHEMBL7520399 | 0.78 | KMT2A (0.52) | KMT2AMEN1ALDH1A1CYP1A2THRB | |
| Oxalic Acid SCHEMBL11437762 | 0.77 | HTT (0.39) | ALDH1A1ABCC4MAPTTSHRHTT | |
| Hydrochloric Acid SCHEMBL28384994 | 0.76 | KMT2A (0.50) | KMT2AMEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL15447196 | 0.74 | NAALAD2 (0.39) | KMT2AMEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL19555034 | 0.72 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL4534531 | 0.72 | TSHR (0.33) | KMT2AMEN1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689890-B2 | Efficient lactam synthesis | UNIVERSITY OF SOUTH FLORIDA | 2004-02-10 | — | — | US | disclosed |
| US-20030171599-A1 | Efficient lactam synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-11 | — | — | US | disclosed |
| US-20030004337-A1 | Efficient lactam synthesis | SOUTH FLORIDA, UNIVERSITY OF | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004337-A1 | Efficient lactam synthesis | COASY, RCE1, DHPS | KMT2A 197/4885MEN1 38/4885ALDH1A1 2347/4885 |
| US-20030171599-A1 | Efficient lactam synthesis | COASY, APH1A, CIAPIN1 | KMT2A 126/4885MEN1 74/4885ALDH1A1 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.