Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ODC1 | P11926 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 5/20 | 0.31 |
| ▸ | ARG1 | P05089 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458161 | 1.00 | MEN1 (0.57) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL30651 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL10692354 | 0.82 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL9586044 | 0.80 | CYP1A2 (0.74) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL7047715 | 0.79 | KMT2A (0.41) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL9236221 | 0.78 | ODC1 (0.58) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL30787966 | 0.77 | ARG2 (0.41) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL10264935 | 0.76 | ARG1 (0.39) | ALDH1A1TSHRODC1ARG2ARG1 | |
| SCHEMBL9457637 | 0.76 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL1416683 | 0.75 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291673-B1 | Folic acid derivatives | PURDUE RESEARCH FOUNDATION | 2001-09-18 | — | — | US | disclosed |
| WO-1999020626-A1 | FOLIC ACID DERIVATIVES | PURDUE RESEARCH FOUNDATION (US) | 1999-04-29 | — | — | WO | disclosed |
| US-5268476-A | Substituted 10bH-oxazolo[3,2-c] [1,3] benzoxazine-2(3H), 5-diones | ABBOTT LABORATORIES (US) | 1993-12-07 | — | — | US | disclosed |
| US-5153358-A | Process for the preparation of alpha-alkylated alpha-amino acids and alpha-halogenated alpha-amino acids | ABBOTT LABORATORIES (US) | 1992-10-06 | — | — | US | disclosed |