Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274289 | 0.86 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL11227523 | 0.83 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL9321639 | 0.81 | CDC7 (0.46) | KDM4EALDH1A1GSK3B | |
| SCHEMBL2454547 | 0.80 | PTGES (0.52) | KDM4EHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7267270 | 0.79 | KDM4E (0.59) | KDM4EHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL28144523 | 0.78 | SCN9A (0.51) | KDM4EHPGDALDH1A1KMT2AGAA | |
| SCHEMBL10561379 | 0.78 | CNR1 (0.51) | KDM4EHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6184613 | 0.76 | KCNMA1 (0.43) | KDM4ESMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL11848374 | 0.76 | ALDH1A1 (0.52) | KDM4EHPGDSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7047758 | 0.75 | KDM4E (0.51) | KDM4EHPGDSMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675578-A2 | USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES | Probiodrug AG (DE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005039548-A2 | USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES | PROBIODRUG AG (DE) | 2005-05-06 | — | — | WO | disclosed |