Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045221 | 0.86 | MRGPRX4 (0.55) | FFAR4HDAC1HDAC2FFAR1HPGD | |
| SCHEMBL7043153 | 0.82 | MMP3 (0.73) | MMP3FFAR4HDAC1HDAC2FFAR1 | |
| SCHEMBL7046517 | 0.82 | ABCB1 (0.52) | MMP3HDAC1HDAC2FFAR1MMP13 | |
| SCHEMBL7048536 | 0.79 | MMP3 (0.79) | MMP3HDAC1HDAC2MMP2MMP1 | |
| SCHEMBL7044314 | 0.78 | HDAC3 (0.49) | HDAC1HDAC2HPGDSMPD1HDAC8 | |
| SCHEMBL7047538 | 0.74 | MMP3 (0.60) | MMP3HDAC1HDAC2MMP2MMP1 | |
| SCHEMBL17231860 | 0.74 | CYP11B1 (0.53) | MMP3FFAR4HDAC1HDAC2FFAR1 | |
| SCHEMBL7047498 | 0.73 | HDAC1 (0.68) | MMP3FFAR4HDAC1HDAC2FFAR1 | |
| SCHEMBL15810332 | 0.73 | HDAC1 (0.55) | MMP3FFAR4HDAC1HDAC2FFAR1 | |
| SCHEMBL7042844 | 0.72 | HDAC2 (0.58) | HDAC1HDAC2FFAR1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874808-B1 | BIPHENYL HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2003-04-09 | — | — | EP | disclosed |
| US-5665777-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1997-09-09 | — | — | US | disclosed |