Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448069 | 0.96 | AGTR1 (0.54) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL9593121 | 0.91 | AGTR1 (0.52) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL6967063 | 0.88 | AGTR1 (0.47) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6968424 | 0.85 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL6959552 | 0.84 | AGTR1 (0.43) | AGTR1ABCC3ABCC2 | |
| SCHEMBL8314073 | 0.82 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9593779 | 0.80 | KDM4E (0.45) | AGTR1AGTR2 | |
| SCHEMBL4943548 | 0.80 | AGTR1 (0.58) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL5498758 | 0.78 | AGTR1 (0.55) | AGTR1ABCC3ABCC2AGTR2 | |
| SCHEMBL6060889 | 0.77 | AGTR1 (0.68) | AGTR1ABCC3ABCC2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565634-B1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | claimed |
| EP-0565634-A1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-20 | — | — | EP | claimed |
| WO-1992010097-A1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-06-25 | — | — | WO | claimed |
| EP-0724387-B1 | ANGIOTENSION II RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CHRONIC ANTI-INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| EP-0565634-B1 | ANGIOTENSIN II RECEPTOR BLOCKING COMPOSITIONS | SMITHKLINE BEECHAM CORP (US) | 1999-03-17 | — | — | EP | disclosed |