Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048382 | 0.91 | AGTR1 (0.58) | AGTR1AGTR2ABCC3ABCC2 | |
| SCHEMBL7448069 | 0.89 | AGTR1 (0.54) | AGTR1AGTR2ABCC3ABCC2 | |
| SCHEMBL6968424 | 0.82 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL6967063 | 0.82 | AGTR1 (0.47) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6959552 | 0.81 | AGTR1 (0.43) | AGTR1ABCC3ABCC2 | |
| SCHEMBL1256316 | 0.81 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9121223 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2ABCC3ABCC2 | |
| SCHEMBL8314073 | 0.79 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9593779 | 0.77 | KDM4E (0.45) | AGTR1AGTR2 | |
| SCHEMBL6959544 | 0.75 | AGTR1 (0.84) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185351-A | Hypotensive agents; for treatment of congestive heart failure, renal failure and glaucoma | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-09 | — | — | US | claimed |