Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048382 | 0.84 | AGTR1 (0.58) | AGTR1ABCC3ABCC2 | |
| SCHEMBL3666088 | 0.82 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9593121 | 0.81 | AGTR1 (0.52) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7448069 | 0.81 | AGTR1 (0.54) | AGTR1ABCC3ABCC2 | |
| SCHEMBL6968424 | 0.79 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL683773 | 0.77 | AGTR1 (0.75) | AGTR1ABCC3ABCC2 | |
| SCHEMBL3630525 | 0.76 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL8314073 | 0.76 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL6967063 | 0.75 | AGTR1 (0.47) | AGTR1ABCC3ABCC2 | |
| SCHEMBL1258093 | 0.74 | MMEL1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955294-B1 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORP (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-0955294-A2 | Imidazolyl-alkenoic acid | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-10 | — | — | EP | disclosed |
| US-5418250-A | Hypotensive | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |