Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.58 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | HTR7 | P34969 | 5/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361080 | 0.99 | HTR6 (0.56) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL3848542 | 0.83 | HTR6 (0.62) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL11364768 | 0.80 | DRD2 (0.58) | DRD2THRBDRD3 | |
| SCHEMBL3846907 | 0.79 | HTR6 (0.60) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL3454087 | 0.78 | HTR6 (0.70) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL12719397 | 0.75 | HTR6 (0.70) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL7044821 | 0.74 | HTR2C (0.48) | HTR6DRD2HTR2CSLC6A4SIGMAR1 | |
| SCHEMBL3846903 | 0.74 | HTR6 (0.65) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL2626629 | 0.74 | HTR6 (0.65) | HTR6DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL3849278 | 0.74 | HTR6 (0.65) | HTR6DRD2HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825202-B2 | CENTRAL NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | SYNTEX (U.S.A.) LLC | 2004-11-30 | — | — | US | disclosed |
| US-20030069254-A1 | New arylsulfonyl derivatives with 5-HT6 receptor affinity | SYNTEX (U.S.A.) LLC | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069254-A1 | New arylsulfonyl derivatives with 5-HT6 receptor affinity | HTR6, HTR1A, HTR4 | HTR6 1/4885DRD2 31/4885HTR1A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.