Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051044 | 1.00 | LMNA (0.35) | LMNAHRH3TSHRALDH1A1TDP1 | |
| SCHEMBL7050630 | 0.98 | LMNA (0.36) | LMNATSHRTDP1ATMCARM1 | |
| SCHEMBL11501574 | 0.82 | LMNA (0.36) | LMNAHRH3TSHRALDH1A1TDP1 | |
| SCHEMBL12718302 | 0.78 | ALDH1A1 (0.37) | LMNAHRH3TSHRALDH1A1MEN1 | |
| SCHEMBL24926235 | 0.76 | HRH3 (0.33) | HRH3TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL6443996 | 0.76 | TSHR (0.36) | HRH3TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11972631 | 0.76 | CYP2D6 (0.41) | LMNAHRH3TSHRALDH1A1TDP1 | |
| SCHEMBL6445428 | 0.76 | TSHR (0.36) | HRH3TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5857647 | 0.76 | TSHR (0.36) | HRH3TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2904075 | 0.76 | HRH3 (0.33) | HRH3TSHRALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114611-A1 | Functionalized alkyllithium formulations with improved thermal stability and processes for making the same | FMC CORPORATION | 2003-06-19 | — | — | US | claimed |
| US-20030114592-A1 | Processes for improving stability of living polymer chain ends | FMC CORPORATION | 2003-06-19 | — | — | US | claimed |
| WO-2000050478-A1 | NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS | FMC CORPORATION (US) | 2000-08-31 | — | — | WO | claimed |
| US-5780551-A | UNSYMMETRICALLY PROTECTED; FROM ONE OR MORE CONJUGATED DIENE OR ALKENYLAROMATIC COMPOUND | FMC CORPORATION (US) | 1998-07-14 | — | — | US | claimed |
| US-20030114611-A1 | Functionalized alkyllithium formulations with improved thermal stability and processes for making the same | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20030114592-A1 | Processes for improving stability of living polymer chain ends | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| WO-2000050478-A1 | NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS | FMC CORPORATION (US) | 2000-08-31 | — | — | WO | disclosed |
| US-5780551-A | UNSYMMETRICALLY PROTECTED; FROM ONE OR MORE CONJUGATED DIENE OR ALKENYLAROMATIC COMPOUND | FMC CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114611-A1 | Functionalized alkyllithium formulations with improved thermal stability and processes for making the same | AAAS, AS3MT, APC | LMNA 892/4885HRH3 4782/4885TSHR 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.