SCHEMBL7050331

SCHEMBL7050331

C=C(Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1)Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.62
PKM P14618 3/20 0.61
GAA P10253 2/20 0.61
POLB P06746 1/20 0.53
MAPT P10636 1/20 0.53
LMNA P02545 1/20 0.43
CA2 P00918 3/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
ENPP2 Q13822 1/20 0.42
ALDH1A1 P00352 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP7 P09237 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3118881 0.85 ELANE (0.63) ELANEPKMGAAPOLBMAPT
SCHEMBL7202624 0.81 ELANE (0.62) ELANEPKMGAAPOLBMAPT
Ammonia Solution, Strong SCHEMBL29108104 0.81 GAA (0.64) ELANEPKMGAAPOLBMAPT
SCHEMBL10721385 0.81 ELANE (0.67) ELANEPKMGAAPOLBMAPT
SCHEMBL5360324 0.80 ELANE (0.61) ELANEPKMGAAPOLBMAPT
SCHEMBL1794823 0.80 ALDH1A1 (0.54) ELANEPKMGAAPOLBMAPT
SCHEMBL8071139 0.79 PKM (0.70) ELANEPKMGAAPOLBMAPT
SCHEMBL5848771 0.79 PKM (0.70) ELANEPKMGAAPOLBMAPT
SCHEMBL31012103 0.79 PKM (0.70) ELANEPKMGAAPOLBMAPT
SCHEMBL8076373 0.79 PKM (0.70) ELANEPKMGAAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999072-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2003-05-02 EP disclosed
US-6303540-B1 CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-10-16 US disclosed
EP-0999072-A1 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-05-10 EP disclosed