SCHEMBL7050797

SCHEMBL7050797

CCC1(CO)COC(=O)C(C)(CC)N1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9735802 0.85 KDM4E (0.31) POLBKDM4EGAA
SCHEMBL7070377 0.81 KDM4E (0.31) POLBKDM4EGAA
SCHEMBL7070464 0.77 KDM4E (0.33) KDM4E
SCHEMBL2394831 0.72 MGLL (0.32) POLBKDM4EGAA
SCHEMBL7068994 0.69
SCHEMBL7067960 0.68 ALDH1A1 (0.34)
SCHEMBL10836554 0.65 ALDH1A1 (0.36)
SCHEMBL5323355 0.65 ALDH1A1 (0.36)
SCHEMBL28740510 0.65 EPHX1 (0.40) POLBKDM4EGAA
SCHEMBL9863702 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015436-B1 MORPHOLINONES AS LIGHT STABILIZERS CIBA SC HOLDING AG (CH) 2003-04-16 EP claimed
EP-1015436-A1 MORPHOLINONES AS LIGHT STABILIZERS Ciba SC Holding AG (CH) 2000-07-05 EP claimed
WO-1999014206-A1 MORPHOLINONES AS LIGHT STABILIZERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-03-25 WO claimed
US-6562815-B1 Stabilizers for organic material against deleterious effects of light, oxygen and/or heat CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US disclosed
EP-1015436-B1 MORPHOLINONES AS LIGHT STABILIZERS CIBA SC HOLDING AG (CH) 2003-04-16 EP disclosed
US-6140326-A FOR STABILIZING AN ORGANIC MATERIAL AGAINST DAMAGE BY LIGHT, OXYGEN AND/OR HEAT CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-10-31 US disclosed
EP-1015436-A1 MORPHOLINONES AS LIGHT STABILIZERS Ciba SC Holding AG (CH) 2000-07-05 EP disclosed
WO-1999014206-A1 MORPHOLINONES AS LIGHT STABILIZERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-03-25 WO disclosed