Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052815 | 0.99 | MAOB (0.50) | MAOBBCL2L1MCL1SMPD1KAT6A | |
| SCHEMBL7047668 | 0.93 | NR4A1 (0.51) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7047717 | 0.93 | SMPD1 (0.50) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7050498 | 0.92 | SMPD1 (0.52) | MAOBBCL2L1MCL1SMPD1KAT6A | |
| SCHEMBL7047657 | 0.91 | SMPD1 (0.53) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7076746 | 0.91 | SMPD1 (0.53) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7080208 | 0.91 | SMPD1 (0.53) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7077945 | 0.91 | SMPD1 (0.53) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7077178 | 0.91 | SMPD1 (0.53) | BCL2L1MCL1SMPD1KAT6AALDH1A1 | |
| SCHEMBL7080258 | 0.91 | SMPD1 (0.53) | BCL2L1MCL1SMPD1KAT6AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191323-A1 | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1300142-A1 | HYPOGLYCEMICS | Ajinomoto Co., Inc. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | MAOB 396/4885BCL2L1 1792/4885MCL1 2343/4885 |
| US-20030191323-A1 | Hypoglycemic agent | GPR119, IAPP, SLC5A2 | MAOB 2736/4885BCL2L1 1489/4885MCL1 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.