Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL3865870 | 1.00 | LMNA (0.42) | LMNATSHRALDH1A1THRBALOX15 | |
| Acrylic Acid SCHEMBL29626859 | 0.85 | LMNA (0.43) | LMNATSHRALDH1A1THRBALOX15 | |
| Methacrylic Acid SCHEMBL3868400 | 0.79 | THRB (0.31) | ALDH1A1THRB | |
| Methacrylic Acid SCHEMBL1877023 | 0.79 | THRB (0.31) | ALDH1A1THRB | |
| SCHEMBL48477 | 0.79 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL29456876 | 0.78 | LMNA (0.46) | LMNATSHRALDH1A1THRBALOX15 | |
| Acrylic Acid SCHEMBL8059326 | 0.74 | LMNA (0.67) | LMNATSHRALDH1A1THRBALOX15 | |
| Acrylic Acid SCHEMBL30880210 | 0.74 | LMNA (0.67) | LMNATSHRALDH1A1THRBALOX15 | |
| Acrylic Acid SCHEMBL8021956 | 0.74 | LMNA (0.67) | LMNATSHRALDH1A1THRBALOX15 | |
| Acrylic Acid SCHEMBL869140 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614418-B2 | MINERAL-LIKE PLASTICS | GHAHARY AKBAR (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-0614418-B1 | MINERAL-LIKE PLASTICS | GHAHARY AKBAR (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5304592-A | Plastic material suspended in thermoplastic matrix | SAFAS CORPORATION | 1994-04-19 | — | — | US | disclosed |