Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360727 | 0.85 | MEN1 (0.49) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL7051039 | 0.84 | ADRB2 (0.54) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL7051037 | 0.84 | ADRB2 (0.54) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL10661432 | 0.83 | ADRB2 (0.49) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL9361467 | 0.81 | NPC1 (0.40) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL11082263 | 0.81 | ADRB2 (0.50) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11092374 | 0.80 | ADRB2 (0.49) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL11812984 | 0.75 | CTSV (0.43) | ADRB3SMN1; SMN2 | |
| SCHEMBL31603899 | 0.74 | CTSV (0.51) | ADRB3 | |
| SCHEMBL3628731 | 0.74 | KMT2A (0.46) | ADRB2ADRB3ADRB1ADRA1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | disclosed |