SCHEMBL7051153

SCHEMBL7051153

ON(Cc1ccc(Br)cc1)Cc1ccc(Br)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 7/20 0.48
MAOB P27338 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TAAR1 Q96RJ0 2/20 0.43
HTR2A P28223 1/20 0.42
CYP2A6 P11509 1/20 0.42
IDO1 P14902 2/20 0.41
CYP1A2 P05177 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8781904 0.76 TSHR (0.46) CYP1A2
SCHEMBL10979593 0.76 ESR1 (0.54) KDM4EALDH1A1TAAR1IDO1
SCHEMBL10748300 0.76 CYP1A2 (0.53) ALDH1A1TAAR1CYP1A2
SCHEMBL7048734 0.74 LPL (0.46) ALDH1A1TAAR1CYP2A6IDO1
SCHEMBL4967718 0.74 CYP2C19 (0.50) PYCR1ALDH1A1TAAR1CYP2A6IDO1
SCHEMBL7047327 0.74 ALDH1A1 (0.48) PYCR1ALDH1A1TAAR1CYP2A6IDO1
SCHEMBL15128047 0.74 PYCR1 (0.67) PYCR1MAOBKDM4EALDH1A1TAAR1
SCHEMBL7047352 0.74 ESR1 (0.57) PYCR1ALDH1A1TAAR1IDO1
SCHEMBL399795 0.74 HRH3 (0.64) PYCR1MAOBKDM4EALDH1A1TAAR1
SCHEMBL12464517 0.74 PYCR1 (0.48) PYCR1MAOBKDM4EALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP claimed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP claimed
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP disclosed
US-6251571-B1 MIXTURE OF OXIDIZER, DYE AND HYDROXYLAMINE E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-26 US disclosed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP disclosed