SCHEMBL7051361

SCHEMBL7051361

CS(=O)(=O)c1cc(N)ccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.57
PDE10A Q9Y233 1/20 0.48
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
CASP1 P29466 2/20 0.44
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP3A4 P08684 2/20 0.44
MEN1 O00255 2/20 0.44
RECQL P46063 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
TNF P01375 1/20 0.44
HSPD1 P10809 1/20 0.44
THRB P10828 1/20 0.44
CYP2C9 P11712 1/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
PTGS2 P35354 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL6251886 0.96 L3MBTL1 (0.53) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL15324899 0.83 L3MBTL1 (0.62) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL17774548 0.83 L3MBTL1 (0.48) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL9367132 0.83 CA1 (0.47) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL177254 0.81 NT5E (0.53) L3MBTL1PDE10AKDM4EALDH1A1CASP1
Hydrochloric Acid SCHEMBL18301892 0.81 CA1 (0.45) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL14576111 0.79 NT5E (0.51) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL17779262 0.79 PDE10A (0.44) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL1913490 0.79 CA1 (0.44) L3MBTL1PDE10AKDM4EALDH1A1CASP1
SCHEMBL3275593 0.78 PTGS1 (0.61) L3MBTL1ALDH1A1ALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9872822-B2 Process for dyeing in the presence of oxidation bases comprising at least one sulfonic, sulfonamide, sulfone, amid or acid group and a metal catalyst, device and ready-to-use composition L'OREAL (FR) 2018-01-23 US disclosed
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION L'OREAL (FR) 2016-05-26 US disclosed
EP-1480604-A1 MOULDING BODY WITH A PEARL LUSTRE PIGMENT Henkel Kommanditgesellschaft auf Aktien (DE) 2004-12-01 EP disclosed
WO-2003074015-A1 MOULDING BODY WITH A PEARL LUSTRE PIGMENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION KRT18, ARSA, SQOR L3MBTL1 4874/4885PDE10A 3327/4885KDM4E 1417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.