SCHEMBL177254

SCHEMBL177254

Nc1ccc(O)c(S(=O)(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.53
RAPGEF4 Q8WZA2 1/20 0.53
ALDH1A1 P00352 8/20 0.50
TDP1 Q9NUW8 5/20 0.50
RECQL P46063 4/20 0.50
CASP6 P55212 3/20 0.50
KDM4E B2RXH2 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
NSD2 O96028 2/20 0.50
POLB P06746 2/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
APEX1 P27695 1/20 0.50
APOBEC3A P31941 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
HSD17B10 Q99714 7/20 0.49
HPGD P15428 3/20 0.49
HIF1A Q16665 2/20 0.49
LMNA P02545 1/20 0.49
DUSP3 P51452 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14576111 0.98 NT5E (0.51) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL9367132 0.84 CA1 (0.47) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL17774548 0.84 L3MBTL1 (0.48) NT5ERAPGEF4ALDH1A1TDP1RECQL
Hydrochloric Acid SCHEMBL18301892 0.83 CA1 (0.45) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL158793 0.83 NT5E (0.53) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL7511717 0.82 RAPGEF4 (0.56) NT5ERAPGEF4ALDH1A1TDP1RECQL
Sulfuric Acid SCHEMBL6251886 0.82 L3MBTL1 (0.53) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL7051361 0.81 L3MBTL1 (0.57) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL29349546 0.80 ALDH1A1 (0.55) NT5ERAPGEF4ALDH1A1TDP1RECQL
SCHEMBL7099533 0.80 RAPGEF4 (0.55) NT5ERAPGEF4ALDH1A1TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106669627-B A kind of adsorption composite material and preparation method thereof 苏州欢颜电气有限公司 2019-07-16 CN claimed
US-20240131109-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING SAME RENOVION, INC. 2024-04-25 US disclosed
US-11938166-B2 Methods and compositions for treating mucosal tissue disorders THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-03-26 US disclosed
US-11890315-B2 Stable ascorbic acid compositions and methods of using same RENOVION, INC. (US) 2024-02-06 US disclosed
WO-2024016019-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF SUBJECTS SUFFERING FROM A SARS-COV-2 INFECTION RENOVION, INC. (US) 2024-01-18 WO disclosed
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2023-06-01 US disclosed
US-20230144527-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING SAME RENOVION, INC. 2023-05-11 US disclosed
US-11602555-B2 Treatment of respiratory tract diseases and infections with ascorbic acid compositions RENOVION, INC. (US) 2023-03-14 US disclosed
US-20220143129-A1 METHODS AND COMPOSITIONS FOR TREATING MUCOSAL TISSUE DISORDERS UNIV NORTH CAROLINA CHAPEL HILL (US) 2022-05-12 US disclosed
US-11058743-B2 Methods and compositions for treating mucosal tissue disorders THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2021-07-13 US disclosed
US-4474697-A DYEING COTTON BAYER AKTIENGESELSCHAFT (DE) 1984-10-02 US disclosed
EP-0084314-A2 Reactive disazo dyes BAYER AG (DE) 1983-07-27 EP disclosed
EP-0013879-B1 REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE FOR DYEING MATERIALS CONTAINING HYDROXYL OR AMIDE GROUPS BAYER AG (DE) 1982-09-15 EP disclosed
US-4270010-A HEATING AN AQUEOUS SOLUTION OF P-AMINOPHENOL OR A SALT WITH AN ORGANIC SULFONIC ACID; SOLVENT EXTRACTION; FROM NITROBENZENE REDUCTION ELPROCHINE AG (CH) 1981-05-26 US disclosed
EP-0015876-A1 Process for the production of hydroquinone ELPROCHINE AG (CH) 1980-09-17 EP disclosed
EP-0013879-A1 Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups BAYER AG (DE) 1980-08-06 EP disclosed
US-4209459-A USEFUL FOR ASSAY OF LEUCIN-AMINOPEPTIDASE ACTIVITY NITTO BOSEKI CO., LTD. (JP) 1980-06-24 US disclosed
US-4104021-A OXIDATION COLOR DYES COMBE INCORPORATED (US) 1978-08-01 US disclosed
US-4010150-A Red copper complexes of disazo compounds containing triazine groups NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-03-01 US disclosed
US-3977826-A HYDROGEN PEROXIDE, OXIDATION DYE COMPONENTS CLAIROL INCORPORATED (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11890315-B2 Stable ascorbic acid compositions and methods of using same GPX1, GSTA1, GPX4 NT5E 2961/4885RAPGEF4 2925/4885ALDH1A1 93/4885
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR NT5E 1901/4885RAPGEF4 3468/4885ALDH1A1 365/4885
US-11602555-B2 Treatment of respiratory tract diseases and infections with ascorbic acid compositions GPX1, GPX4, GSR NT5E 1901/4885RAPGEF4 3468/4885ALDH1A1 365/4885
US-20240131109-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING SAME GPX1, GSTA1, GPX4 NT5E 2961/4885RAPGEF4 2925/4885ALDH1A1 93/4885
US-20230144527-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING SAME GPX1, GSTA1, GPX4 NT5E 2961/4885RAPGEF4 2925/4885ALDH1A1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.