SCHEMBL17779262

SCHEMBL17779262

CNS(=O)(=O)c1cc(N)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.44
TSHR P16473 2/20 0.43
FTO Q9C0B1 1/20 0.43
LMNA P02545 1/20 0.41
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 3/20 0.40
RECQL P46063 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CASP1 P29466 2/20 0.40
ALOX15 P16050 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TNF P01375 1/20 0.40
CYP3A4 P08684 1/20 0.40
HSPD1 P10809 1/20 0.40
THRB P10828 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5203092 0.81 PTGS1 (0.55) TSHRFTOLMNAALDH1A1RECQL
SCHEMBL328220 0.79 LMNA (0.65) TSHRLMNAALDH1A1KDM4ERECQL
SCHEMBL32664450 0.79 GAA (0.48) TSHRFTOLMNAALDH1A1TDP1
SCHEMBL29626631 0.79 LMNA (0.65) TSHRLMNAALDH1A1KDM4ERECQL
SCHEMBL10868958 0.79 GAA (0.48) TSHRFTOLMNAALDH1A1TDP1
SCHEMBL7051361 0.79 L3MBTL1 (0.57) PDE10ATSHRALDH1A1KDM4ERECQL
SCHEMBL17774548 0.78 L3MBTL1 (0.48) PDE10ATSHRLMNAALDH1A1KDM4E
SCHEMBL9367132 0.78 CA1 (0.47) PDE10ATSHRALDH1A1KDM4ERECQL
SCHEMBL25341310 0.78 WDR5 (0.56) MAPT
SCHEMBL1805587 0.78 ALOX5AP (0.41) LMNAALDH1A1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION L'OREAL (FR) 2016-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160143826-A1 PROCESS FOR DYEING IN THE PRESENCE OF OXIDATION BASES COMPRISING AT LEAST ONE SULFONIC, SULFONAMIDE, SULFONE, AMID OR ACID GROUP AND A METAL CATALYST, DEVICE AND READY-TO-USE COMPOSITION KRT18, ARSA, SQOR PDE10A 3327/4885TSHR 3932/4885FTO 246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.