Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051488 | 1.00 | APP (0.47) | APPSENP1GSK3BBACE1LTA4H | |
| SCHEMBL7051378 | 0.78 | THRB (0.49) | — | |
| SCHEMBL7051375 | 0.78 | THRB (0.49) | — | |
| SCHEMBL7048203 | 0.77 | MEN1 (0.47) | — | |
| SCHEMBL7051491 | 0.76 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL7051490 | 0.76 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL6546898 | 0.75 | GSK3B (0.67) | APPGSK3BBACE1 | |
| SCHEMBL6546896 | 0.75 | GSK3B (0.67) | APPGSK3BBACE1 | |
| SCHEMBL18655903 | 0.74 | LTB4R (0.51) | — | |
| SCHEMBL6545867 | 0.74 | ABCB1 (0.50) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | JOMAA PHARMAKA GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | HRH2, ASPH, NQO2 | APP 3007/4885SENP1 4534/4885GSK3B 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.