Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 8/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617658 | 0.73 | SENP1 (0.42) | SENP1ESR1ESR2HSD17B10CYP3A4 | |
| SCHEMBL13609966 | 0.73 | ESR2 (0.60) | SENP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19901328 | 0.72 | PDE4B (0.51) | SENP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9424416 | 0.72 | ALDH1A1 (0.42) | SENP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13609974 | 0.70 | ESR1 (0.65) | ESR1ESR2HSD17B10CYP3A4AR | |
| SCHEMBL28649969 | 0.68 | ESR1 (0.62) | ESR1ESR2HSD17B10CYP3A4AR | |
| SCHEMBL7858676 | 0.68 | TYR (0.54) | SENP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5890294 | 0.68 | NQO1 (0.62) | SENP1ESR1ESR2HSD17B10CYP3A4 | |
| SCHEMBL11806020 | 0.68 | SENP1 (0.37) | SENP1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8617662 | 0.67 | ESR1 (0.54) | SENP1ESR1ESR2HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003022563-A1 | LOW PERMEATION NITRILE-BUTADIENE RUBBER TUBE WITH ALUMINUM BARRIER LAYER | DAYCO PRODUCTS, LLC (US) | 2003-03-20 | — | — | WO | claimed |
| US-20030049401-A1 | Low permeation nitrile-butadiene rubber tube with aluminum barrier layer | DAYCO PRODUCTS, LLC | 2003-03-13 | — | — | US | claimed |