Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 7/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057845 | 0.88 | UBE2M (0.43) | KDM4EUBE2MDCUN1D1POLBADORA2A | |
| SCHEMBL7051852 | 0.87 | UBE2M (0.40) | UBE2MDCUN1D1MLNR | |
| SCHEMBL7056211 | 0.83 | UBE2M (0.45) | UBE2MDCUN1D1MLNR | |
| SCHEMBL7057300 | 0.81 | MLNR (0.43) | KDM4EDCUN1D1DRD2MLNRCYP3A4 | |
| SCHEMBL7057309 | 0.78 | UBE2M (0.43) | KDM4EUBE2MDCUN1D1MAPK1BCHE | |
| SCHEMBL7056568 | 0.78 | DRD2 (0.58) | KDM4EMAPK1HSD17B10POLBBCHE | |
| SCHEMBL3196517 | 0.71 | SLC6A4 (0.41) | — | |
| SCHEMBL7051610 | 0.71 | DRD2 (0.60) | DRD2 | |
| SCHEMBL6659850 | 0.70 | TDP1 (0.49) | KDM4EMAPK1HSD17B10POLBCYP3A4 | |
| SCHEMBL7055291 | 0.69 | GRIN2B (0.40) | UBE2MDCUN1D1DRD2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |