Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057309 | 0.80 | UBE2M (0.43) | DRD2KDM4EBCHEACHEALDH1A1 | |
| SCHEMBL7051602 | 0.78 | KDM4E (0.42) | DRD2POLBKDM4EBCHEACHE | |
| SCHEMBL7057845 | 0.77 | UBE2M (0.43) | POLBKDM4E | |
| SCHEMBL7051852 | 0.76 | UBE2M (0.40) | — | |
| SCHEMBL7056211 | 0.74 | UBE2M (0.45) | HTTTSHRNPSR1 | |
| SCHEMBL7057300 | 0.74 | MLNR (0.43) | DRD2DRD3KDM4ECYP3A4CYP2D6 | |
| SCHEMBL7056570 | 0.73 | DRD2 (1.00) | DRD2DRD3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3196517 | 0.71 | SLC6A4 (0.41) | ALDH1A1HTTNPC1 | |
| SCHEMBL1645759 | 0.69 | DRD2 (0.52) | DRD2ALDH1A1GAAHSD17B10SMN1; SMN2 | |
| SCHEMBL6659850 | 0.69 | TDP1 (0.49) | POLBDRD3KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |