Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057848 | 0.87 | DRD2 (0.59) | DRD2ALDH1A1HTR1AHTR7HRH1 | |
| SCHEMBL7051849 | 0.85 | DRD2 (0.57) | DRD2ALDH1A1HTR1AHTR7HRH1 | |
| SCHEMBL7056214 | 0.81 | DRD2 (0.55) | DRD2ALDH1A1HTR1AHTR7HRH1 | |
| SCHEMBL7057303 | 0.79 | DRD2 (0.55) | DRD2ALDH1A1HTR1AHTR7HRH1 | |
| SCHEMBL7057313 | 0.76 | DRD2 (0.62) | DRD2 | |
| SCHEMBL29459507 | 0.76 | HTR1A (0.62) | DRD2ALDH1A1HTR1AHTR7HRH1 | |
| SCHEMBL26992312 | 0.76 | HTR1A (0.62) | DRD2ALDH1A1HTR1AHTR7HRH1 | |
| SCHEMBL7056570 | 0.75 | DRD2 (1.00) | DRD2ALDH1A1HTR1AHTR7DRD3 | |
| SCHEMBL14028451 | 0.75 | HTR1A (0.79) | DRD2HTR1ADRD3 | |
| SCHEMBL5730330 | 0.74 | HTR1A (0.63) | DRD2ALDH1A1HTR1AHTR7HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |