Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971718 | 0.84 | CCR3 (0.66) | CCR3DRD2ACHE | |
| SCHEMBL7055295 | 0.84 | DRD2 (0.55) | CCR3DRD2ACHE | |
| SCHEMBL6219793 | 0.81 | DRD2 (0.63) | CCR3DRD2ACHE | |
| SCHEMBL7056235 | 0.81 | DRD2 (0.55) | CCR3DRD2ACHE | |
| SCHEMBL7057303 | 0.80 | DRD2 (0.55) | CCR3HTR2ADRD2 | |
| SCHEMBL7057916 | 0.80 | HRH1 (0.59) | CCR3DRD2 | |
| SCHEMBL7053892 | 0.78 | HTR1A (0.69) | HTR2ADRD2 | |
| SCHEMBL31026378 | 0.78 | HTR1A (0.69) | HTR2ADRD2 | |
| SCHEMBL21997738 | 0.75 | CASP3 (0.55) | — | |
| SCHEMBL236787 | 0.75 | TDP1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |