Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7054302 | 0.99 | HTR1A (0.67) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL7049865 | 0.92 | HTR1A (0.80) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| Hydrochloric Acid SCHEMBL7053164 | 0.91 | HTR1A (0.79) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL7054044 | 0.90 | HTR1A (0.69) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL8875520 | 0.90 | HTR1A (0.84) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL7048055 | 0.90 | HTR1A (0.53) | HTR1AADRA1AADRA1DADRA1BSMN1; SMN2 | |
| SCHEMBL8876429 | 0.88 | HTR1A (0.71) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL8875767 | 0.86 | HTR1A (0.77) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL7051606 | 0.86 | HTR1A (0.72) | HTR1AADRA1AADRA1DADRA1BLMNA | |
| SCHEMBL7048075 | 0.84 | HTR1A (0.80) | HTR1AADRA1AADRA1DADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | claimed |
| EP-1222183-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-07-17 | — | — | EP | claimed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | claimed |
| WO-2001029022-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-04-26 | — | — | WO | claimed |