Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 9/20 | 0.43 |
| ▸ | HTR2C | P28335 | 9/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052255 | 0.90 | HTR1A (0.68) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7051161 | 0.89 | ADRA1D (0.64) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| Hydrochloric Acid SCHEMBL7054302 | 0.89 | HTR1A (0.67) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7050780 | 0.86 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL7050907 | 0.83 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL7051822 | 0.82 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL7052077 | 0.82 | HTR1A (0.64) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL7052416 | 0.82 | ADRA1D (0.55) | HTR1AADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL7049769 | 0.81 | HTR1A (0.63) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL7049865 | 0.81 | HTR1A (0.80) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | claimed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | claimed |
| EP-1222183-B1 | BENZOPYRAN DERIVATIVES | RECORDATI CHEM PHARM (IT) | 2003-04-23 | — | — | EP | disclosed |
| EP-1222183-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 2002-07-17 | — | — | EP | disclosed |
| US-6403594-B1 | UROGENTIAL INFECTIONS, ETC | RECORDATI, S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2002-06-11 | — | — | US | disclosed |
| WO-2001029022-A1 | BENZOPYRAN DERIVATIVES | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) | 2001-04-26 | — | — | WO | disclosed |